Exosome-Based Treatment for Atopic Dermatis'
ExoCoBio Inc., based in South Korea, published a scientific
paper on that stem cell-derived exosomes dramatically relieves
atopic dermatitis and inhibits a variety of inflammatory targets in
the journal of Stem Cell Research and Therapy.
According to the paper, the symptoms of mice having severe
atopic dermatitis were significantly improved after administration of
stem cell-derived exosomes intravenously or subcutaneously, so that
the level of serum immunoglobulin E (IgE), the number of eosinophils
in blood, and the number of mast cells in the skin lesion were
decreased. It has also been found that the number of inflammatory
dendritic epidermal cells (IDECs), which are not found in normal skin
but cause an allergic inflammatory response in atopic dermatitis
lesions, also significantly decreased to a normal skin level after
administration of stem cell-derived exosomes. In addition, the
improvement of the symptoms by stem cell-derived exosomes
was comparable to that of a steroid drug, Prednisolone.
<CISION> PRweb 2018. 8.24